If you're new to managing payroll within Cintra iQ, here is a list of information you will need to input each payroll period. Please note that you may do things slightly differently in your organisation.

Make contractual changes that affect pay
Manage employee post changes: See How do I create/assign a post? and How do I assign spine points to employee posts?
Employee Payments & Rates: See How do I input variable payments and rates for the current period? and How do I add adjustments to employees?
Manage absences
Update pension/benefits contribution data
Make Tax & NI changes
Input variable payments or deductions for the period